Incluye referencias bibliográficas e índice CONTENIDO: The basic concepts and tools -- Conceptual toolkit: The molecular principles for understanding proteins -- The key mathematical tools -- Calculations in the molecular biosciences; Part 1 Characterisation of molecular components -- Calculations in the molecular biosciences: Part 2 Characterisation of processes -- Sect. B Goals and methods. The important properties of proteins and how to explore them -- Sect. C Data analysis in practice. Analytical methods -- Purification of proteins -- Determination of protein structure -- Enzyme activity and mechanism -- Binding of ligands to proteins -- How to report experimental work.