Incluye referencias bibliográficas e índice. CONTENIDO: Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- One-compartment open model : intravenous bolus administration -- Multicompartmental models : intravenous bolus administration -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Drug elimination and hepatic clearance -- Pharmacogenetics -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design and in vitro drug product performance -- Drug product performance, in vivo: Bioavailability and bioequivalence -- Impact of drug product quality and biopharmaceutics on clinical efficacy -- Modified-release drug products -- Targeted drug delivery systems and biotechnological products -- Relationship between pharmacokinetics and pharmacodynamics -- Application of pharmacokinetics in clinical situations -- Dose adjustment in renal and hepatic disease -- Physiological pharmacokinetic models, mean resident time, and statistical moment theory -- App. A Statistics -- App. B Applications of computers in pharmacokinetics -- App. C Ethical considerations -- App. D Solutions to frequently asked questions (FAQ) and learning questions -- App. E Popular drugs and pharmacokinetic parameters.
Forma Variante de Título: Applied biopharmaceutics and pharmacokinetics